About Us

The MGB Pituitary Center of Excellence provides a multidisciplinary approach to patients with pituitary and hypothalamic disorders, with evaluation and treatment by a team of endocrinologists, neurosurgeons, and radiation oncologists. The Center is an international referral center for the evaluation and treatment of pituitary tumors and disorders of the hypothalamic-pituitary region. The Center is ideally suited for the referral of patients with pituitary tumors, including prolactinomas, Cushing's disease, acromegaly, nonfunctioning pituitary tumors, recurrent pituitary adenomas, and pituitary and hypothalamic disorders. Patients may be referred for the development of a treatment plan in conjunction with their primary physicians, for second opinions, or for ongoing management by the Center physicians.

A nurse speaking with a patient in an exam room in a pituitary clinic

Services

  • Endocrinologists are experienced in the evaluation and treatment of all facets of pituitary disease, including advanced diagnostic techniques, hormone replacement therapy, and medical management of pituitary disorders. They are involved in clinical research on investigational drugs for the treatment of Cushing's disease, acromegaly, and other conditions.

  • Neurosurgeons provide expert surgical intervention when necessary.

  • Radiation oncologists facilitate the planning of radiation therapy.

  • The MGB Pituitary Center nursing team offers patient education, including teaching self-administration of medications requiring injection, and performs sophisticated endocrine testing in our testing center.

Pituitary neurosurgeons operating on a patient; transsphenoidal surgery

We Offer State-of-the-Art:

  • Diagnostic testing, including complex endocrine testing in our testing center and inferior petrosal sinus sampling (IPSS) for patients with Cushing's syndrome

  • Neurosurgical interventions, including use of minimally-invasive endoscopic endonasal technique with dual ENT/neurosurgery team and access to intraoperative MRI

  • Radiation treatment

  • Research and educational opportunities, including a weekly multidisciplinary clinical case conference

A patient at Massachusetts General Hospital receiving radiation therapy; radiation oncology; pituitary tumors

MGB Pituitary Center of Excellence Services Overview

  • The MGB Pituitary Center offers:

    • Detailed outpatient evaluations of all disorders affecting the hypothalamus and pituitary gland

    • Complete basal and dynamic hormone testing

    • Coordination of endocrine evaluations, radiological studies, visual field testing, and surgical and radiation treatment consultations.

    • A diagnostic and therapeutic plan formulated for each patient and provided to the referring physician

    • A weekly multidisciplinary case conference at which complex cases are presented

    • The opportunity to participate in clinical research designed to enhance the care of patients with pituitary disorders

    • Workshops for patients and families

  • The MGB Pituitary Center works with referring physicians to provide the following:

    • Consultative evaluations of patients with pituitary disorders

    • Complete basal and dynamic hormone testing

    • Coordination of endocrine evaluations, radiological studies, visual field testing, and surgical and radiation therapy consultations

    • A diagnostic and therapeutic plan formulated for each patient and provided to the referring physician

    • A weekly multidisciplinary case conference at which complex cases are presented (outside physicians are also welcome to present their cases)

    • A research program designed to enhance the care of patients with rare pituitary disorders

    • Medical education specifically in the area of pituitary disorders, including educational presentations by our faculty and postgraduate educational opportunities

    In response to continuing developments of new treatments for patients with pituitary disease, the MGB Pituitary Center offers an Information Service for Physicians. The purpose is to support physicians in the care of their patients by providing access to the most recent information and research regarding pituitary disease and its treatment.

    Physicians with questions may contact Dr. Beverly MK Biller at 617-726-3965 or 1-888-429-6863 or by email pituitary.info@partners.org

    Physicians with questions about pituitary neurosurgery may contact Daniela Berner at dberner@bwh.harvard.edu

  • We are actively recruiting participants for clinical and basic research studies, and we hope that you will consider participating. These studies are designed to advance our understanding of pituitary disorders and improve treatment for pituitary patients.

  • Patient Education:

    Physician Education:

    • The MGH/Harvard Medical School postgraduate course Clinical Endocrinology is held annually virtually and includes a full day on pituitary topics. Check back later for a link to register for 2026, but for now, save the dates: March 21 - 25, 2026

  • To request an appointment, contact:

    • Massachusetts General Hospital Campus: (617) 726-7948 (Endocrinology) or (617) 724-9117 (Neurosurgery)

    • Brigham and Women’s Campus: (617) 732-6679 (Endocrinology) or (617) 525-3060 (Neurosurgery)

    Physicians with questions may email pituitary.info@mgb.org.

    The following information may be required prior to your appointment:

    • Copies of your medical records/discharge summary/physician notes/medication list

    • A copy of your MRI or CT images on a CD

    • A copy of your lab reports

    • A list of questions to ask your doctor

    Our clinic staff will help you update your hospital registration and insurance information.

A Look Inside the Center

Entrance to the Neuroendocrine & Pituitary Tumor Clinical Center with signs and flower decorations on the glass.
Three medical professionals sitting and smiling in an office setting with computers and paperwork.
Three women posing together in a hallway with brick walls, wearing ID badges. Two women are in gray jackets, and one is in a red dress.
Reception area of a clinical center with a desk, protective glass, water cooler, and wall sign for "Neuroendocrine & Pituitary Tumor Clinical Center."
Two nurses attend to a patient in an exam room. The patient is seated while one of the nurses draws blood from her arm.
Two women smiling in a professional office setting, one wearing a plaid blazer and glasses, the other in a white lab coat.